Learn about ACTEMRA® treatment for rheumatoid arthritis, giant cell arteritis, systemic juvenile idiopathic arthritis, and polyarticular juvenile idiopathic arthritis. Find instructions for ACTEMRA® (tocilizumab) subcutaneous injections and helpful information on the ACTEMRA® Medication Guide that should help you better. Inside this kit you’ll also find: .. Some patients may be eligible for free drug through the .. Use a quick, dart-like motion to insert the needle all the way into.
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Physicians are encouraged to register patients and pregnant women are encouraged to register themselves by calling In the open-label extension over an average duration of 73 weeks of treatment, the overall rate of infections was per patient-years.
Contact immediately, pakcage well as your healthcare provider or nurse, if you experience any of these reactions:.
Genentech does not recommend and does not endorse the content on any third-party inserh. Members have access to online educational resources and treatment management tools.
The link you have selected will take you away from this site to one that is not owned or controlled by Genentech, Inc. Reviewing the Inserg Guide should help you to better understand the risks and benefits of your RA treatment.
Patient Education and Training
Reporting side effects Tell your healthcare provider right away if you are experiencing any side effects. In the 6-month control period, in SC-I, the frequency of injection-site reactions was Serious allergic reactions, including death, can happen with ACTEMRA infusions or injections, even if they did not occur with an earlier infusion or injection. Your healthcare provider may stop your ACTEMRA treatment for a period of time or change your dose of medicine if needed because of changes in these blood test results.
The most common serious infections included pneumonia, urinary tract infection, cellulitis, herpes zoster, gastroenteritis, diverticulitis, sepsis and bacterial arthritis. Neutrophils are white blood cells that help the body fight infection low platelet count.
Your cholesterol levels should be checked 4 to 8 weeks after the start of your treatment, and then every 6 months after that. ACTEMRA is an immunosuppressant, and treatment with immunosuppressants may result in an increased risk of malignancies. Your healthcare provider should do blood tests to check your cholesterol levels 4 to 8 weeks after you start receiving ACTEMRA, and then every 6 months after that You should not receive ACTEMRA if your neutrophil and platelet counts are too low or your liver function test levels are too high.
The risks and benefits of treatment with ACTEMRA should be carefully considered prior to initiating therapy in patients with chronic or recurrent infection. The limited available data with ACTEMRA in pregnant women are not sufficient to determine whether there is a drug-associated risk for major birth defects and miscarriage.
Subcutaneous Injections for RA | ACTEMRA® (tocilizumab)
For ACTEMRA subcutaneous injection, advise patients to seek immediate medical attention if they experience any symptoms of a hypersensitivity reaction.
Dosage modifications may be required. The purpose of this registry is to check the health of the pregnant mother and her baby. Events of gastrointestinal GI perforation have been reported in clinical trials, primarily as complications of diverticulitis in RA patients. Tell your healthcare provider right away if you see any signs of these symptoms: Your use of third-party websites is at your own risk and subject to the terms and conditions of use for such sites.
ACTEMRA is indicated for the treatment of active polyarticular juvenile idiopathic arthritis in patients 2 years of age and older.
Pacmage Stomach-area pain that does not go away Change in your bowel habits. Most common side effects Tell your healthcare provider if you have these or any other side effect that bothers you or does not go away: This happens most often in people who also take nonsteroidal anti-inflammatory drugs NSAIDscorticosteroids, or methotrexate.
Infusion Reactions In PJIA patients, infusion-related reactions are defined as all events occurring during or within 24 hours of an infusion. Genentech does not recommend and does not endorse the content on any third-party websites. inserr
This can make you more likely to get infections or make any current infection worse. This happens most often in people who also take nonsteroidal anti-inflammatory drugs NSAIDscorticosteroids, or methotrexate. Tell your healthcare provider right away if you see any of these side effects: You should not do both.
Tell your healthcare provider right away if you are experiencing any side effects. Cytochrome Ps in the liver are down-regulated by infection and inflammation stimuli including cytokines such as IL The information contained in this section of the site is intended for U. Patients treated with ACTEMRA are at increased risk for developing serious infections that may lead to hospitalization or death, including tuberculosis TBbacterial, invasive fungal, viral, or other opportunistic infections.
Moderate to Severe Rheumatoid Arthritis. These ISRs occurred in a greater proportion of patients at or above 30 kg If you have polyarticular juvenile idiopathic arthritis PJIA you will have blood tests done every 4 to 8 weeks during treatment. If you had hives, a rash, or experienced flushing after injecting, you should tell your healthcare provider pakage nurse actrmra your next injection.