Sea como fuere, el tratamiento prolongado con nitratos se suele acompañar de En aquellos pacientes que presentan angina de Prinzmetal sobre un fondo de . We present 2 cases of severe vasospastic angina resistant to intensive medical vagal tone associated with thyrotoxicosis triggers prinzmetal variant angina and Un tratamiento a tener en cuenta en la tirotoxicosis inducida por amiodarona. S: Coronary arterial spasm and Prinzmetal’s variant form of angina induced by hyperventilation and Tris-buffer infusion. Circulation 56, A lead ECG was obtained. From the Cattedra di Fisiopatologia Cardiorespiratoria dell.

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Previous article Next article. The free thyroxine level was 6. Two weeks later, he was readmitted with the same clinical signs and symptoms and the same electrical changes, accompanied by anxiety and resting tremor.

The atenolol that had originally been prescribed was discontinued. Finally, the patient underwent total thyroidectomy, without subsequent recurrence of anginal episodes, even after fksiopatologia calcium antagonists were discontinued 2 months after the surgical procedure.

Thyrotoxicosis-Induced Vasospastic Angina | Revista Española de Cardiología (English Edition)

For the management of this entity, it is essential to control the thyroid lrinzmetal, which can be curative in itself, obviating the need df subsequent antianginal therapy, 5 especially if there is no accompanying heart disease. The episodes of angina at rest were uncontrollable until diagnosis and proper treatment of the concomitant hyperthyroidism, the onset of which was nearly asymptomatic.


A repeated coronary angiography revealed a diffuse, severe spontaneous spasm of anterior descending artery ADA Figure 1which reproduced the admission clinical onset.

The journal adheres to the standards of academic research publications in all aspects including peer-review and ethical principles. Thus, we highlight the importance of determining thyroid hormone fisiopatoloogia in cases of vasospastic angina, especially when drug resistance is observed, 4 and even if the signs of hyperthyroidism are mild, 2 a circumstance to which previous treatment with beta-blockers can contribute.

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Angina de Prinzmetal & Sd de Takotsubo by Diego Cañar on Prezi

A second catheterization ruled out complications associated with the previously implanted stentas well a development of new lesions, and the patient was discharged on calcium antagonists and nitrates. Hospital General Universitario de Alicante. He underwent primary angioplasty with conventional stent implantation in mid ADA.

With a diagnosis of Graves’ disease, the hyperthyroidism was controlled with carbimazole, and the patient has remained asymptomatic after 8 months of follow-up with no need for calcium antagonists, which were discontinued 45 days after he was discharged.


One year after the initiation of this medication, he was admitted to the hospital with unstable angina, with mild electrical and enzymatic changes.

Thyrotoxicosis-Induced Vasospastic Angina

December Next article. Forty-eight hours later, a level of free thyroxine of 4. We present 2 cases of severe vasospastic angina resistant to intensive medical treatment.

A year-old man was brought to our hospital with acute myocardial infarction and precordial ST elevation. From Monday to Friday from 9 a.

Three months after the procedure, he was readmitted with unstable angina after detection of transient precordial ST elevation and slight enzymatic elevation. Se continuar a navegar, consideramos que aceita o seu uso. The duration of the follow-up period was 14 months. These manuscripts contain updated topics with a major clinical xngina conceptual relevance in modern medicine.

The patient was a year-old man with dilated cardiomyopathy and angiographically normal coronary arteries in 2 prior catheterizations. Iberoamerican Cardiovascular Journals Editors’ Network. The present manuscript strengthens the hypothesis concerning causality in the association between hyperthyroidism and vasospastic angina, which, if sufficiently prolonged, can provoke myocardial infarction.