J Neurol Sci. Jan 21;(1) Clinical diagnosis in Karwinskia humboldtiana polyneuropathy. Martínez HR(1), Bermudez MV, Rangel-Guerra RA. Toxicon. May;53(6) doi: /n Karwinskia humboldtiana (buckthorn) fruit causes central nervous system damage during. Karwinskia humboldtiana. Karwinskia humboldtiana (Schult.) Zucc. Coyotillo, Humboldt Coyotillo. Rhamnaceae (Buckthorn Family). Synonym(s).

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This is the first report about the presence of neuronal damage caused by Kh in the Central Nervous System in chronic intoxication. By using this site, you agree to the Terms of Use and Privacy Policy. Indeed, the Tepehuan boil the bark for several hours and ingest the resultant tea for fevers, identical uses to the Tarahumara that the ethnographer duly noted Pennington ; We conclude that this intoxication is common in Mexico.

But an experiment conducted on livestock clearly illustrates how the dangers of coyotillo fruit. It is native to southern and western Texas in the United States [2] as well as much of Mexico. Journal of Neurological Science 1: Kzrwinskia Cebuano Svenska Winaray Edit links. The fruit is the most poisonous part of the Coyotillo plant, or, at least the seed inside the fruit.

Intoxication with buckthorn (Karwinskia humboldtiana): report of three siblings.

This page was last edited on 25 Augustat Spasms and paralysis in the extremities are the first observable symptoms of coyotillo poisoning, which often spreads to affect breathing or liver function, ending in death. It only takes 0. Additionally, a cooked potion of the leaves was applied externally to infected wounds Martinez Articles with ‘species’ microformats Commons category link from Wikidata Commons category link is on Wikidata All stub articles.

Their Environment and Material Culture. Children exhibiting symptoms of coyotillo poisoning, including shakes or “palsies” were seen by outside observers.


Lady Bird Johnson Wildflower Center – The University of Texas at Austin

Wikimedia Commons has media related to Karwinskia humboldtiana. Despite its toxic properties, parts of the coyotillo plant was used for medicinal purposes and, perhaps, even as starvation karwindkia by one group. Coyotillo is commonly found across northern Mexico in limestone soils, including the states of Nuevo Leon, Coahuila, Chihuahua, and Sonora, but it grows throughout much of Mexico.

With this methodology, we found lesions in the motor pathway. Small wonder so many children humboldttiana Mexico are poisoned by this common and deadly shrub. However, the leaves and the fruit, especially the seed inside the exocarp contain deadly neurotoxins. The Tepehuan also report using the fruit as a starvation food.

In other projects Wikimedia Commons Wikispecies. My concern is that the relaxation might well be permanent.

Coyotillo, Tullidora

Coyotillo, Tullidora Karwinskia humboldtiana Schult. Studies have shown that the coyotillo T neurotoxin is detectable in the bloodstream of victims, which is important because the symptoms may be caused by other pathologies Martinez, et al. However, raccoon, coyote, and fox appear to eat the berries and survive, because the scat of these animals is loaded with humoldtiana seeds when the fruit is ripe. All six cases survived, with complete recovery in five.

It was actually eaten as starvation karwniskia in June, but over-consumption caused a serious stomach ache. Electrodiagnostic studies were performed, including motor conduction velocities, distal latencies, F-wave latency and compound muscle action potential CAMP amplitude.

New York, New York: These cases had a symmetric motor polyneuropathy with the absence of tendon reflexes and no sensory signs or cranial nerve involvement. Coyotillo is a small, evergreen shrub with deep green, almost glossy and distinctively veined leaves that grow opposite each other along the stem.

Only one patient required assisted ventilation due to bulbar paralysis. The presence of Karwinskia humboldtiana toxins in blood were determined by thin layer chromatography.

Coyotillo is a very poisonous plant, and stockmen know to introduce only livestock that are familiar with the vegetation of the region, or to feed plenty of supplements to those animals that aren’t.


We designed an open trial at the Pediatric Neurology service and included all cases with acute ascending paralysis that were admitted to our hospital in the last two years.

I do not know how lethal coyotillo is in humans, but 0. We present our experience in the clinical diagnosis of Karwinskia humboldtiana polyneuropathy, as confirmed by toxin detection in blood.

In this polyneuropathy the lesion demyelization in peripheral nerves has been described in several animal species, both in acute and in chronic intoxication. From Wikipedia, the free encyclopedia. However, it often takes days or even weeks after consumption for the symptoms to manifest. Goats, sheep, and cattle are all susceptible Lyons and Machen The Tarahumara crushed coyotillo bark to prepare a tea that was ingested for fevers.

There is a curious and telling reference to coyotillo use by the Tarahumara. In conclusion, although the native poeples of the Lower Pecos Canyonlands apparently did use Coyotillo in some way, it is a highly dangerous plant.

This Rhamnaceae article is a stub. Despite its deservedly poisonous reputation, coyotillo seeds, branches, and leaves were recovered from Early Archaic, Middle Archaic, and Late Archaic contexts at Hinds Cave Dering The poisoning manifests itself as ascending paralysis, starting in the extremities and moving toward the trunk, and in extreme cases victims need mechanical assistance to breathe. Karwinskia humboldtiana Scientific classification Kingdom: Ingestion of the fruit causes damage to nerves as well as the pulmonary system and the liver.